Vergara plays Alicia Oviedo in the television show Amas de Casa Desesperadas, the Colombian version of Desperate Housewives. Her character is essentially the Colombian counterpart to the Mary Alice Young character in the American show. She also appeared on the ABC drama Dirty Sexy Money as Jeremy Darling's love interest. Vergara has made guest appearances in the Mexican telenovela Fuego En La Sangre.
In 2009, Vergara had a five-week stint on Broadway as "Mama" Morton in the revival of Chicago.
In 2011, Vergara was supposed to star in The Paperboy, an independent drama directed by Lee Daniels. Due to delays, shooting was pushed back a week (which conflicted with Vergara shooting Season 3 of Modern Family), so she was forced to drop out.
In July 2011, she finished filming for the Farrelly Brothers’ The Three Stooges, her first lead role in a film. Vergara said, "I play a mean woman that tries to manipulate the Three Stooges into killing her husband so that she gets all the money.
